![]() Never take your medications with grapefruit before checking with your pharmacist or physician. ![]() Drugs that interact with grapefruit juice Patients treated with certain medications may have to avoid other fruits and their juices (e.g., starfruit, pomegranate). Most citrus fruit, including lemons, sweet oranges (Navel or Valencia) and tangerines are considered safe. Seville oranges (used in marmalade), limes and pomelos may produce similar effects to grapefruit. Antibiotics and common pain relievers also can cause the blood to thicken. Vitamin supplements can also disrupt a carefully balanced dosage of medication. Gandy said food isn’t the only thing to be cautious of when taking blood thinners, also called anticoagulants. To minimize the risk of drug interaction, refrain from eating grapefruits or drinking grapefruit juice if you are taking one of the following drugs. Interactions from Supplements and Other Medications. ![]() Breast cancer: There is concern about the safety of drinking excessive amounts of grapefruit juice. Not everyone will react the same way it depends on which drug is involved, the grapefruit itself, and how sensitive you are to these effects. Pregnancy and breast-feeding: Not enough is known about the use of grapefruit during pregnancy and breast-feeding.Stay on the safe side and avoid use. Some drugs that treat high blood pressure, such as Procardia and Adalat CC (both nifedipine). Grapefruit interactions are highly unpredictable. Which medications should not be taken with grapefruit Some statin drugs to lower cholesterol, such as Zocor (simvastatin) and Lipitor (atorvastatin). Drinking grapefruit juice in the morning, for example, and then taking your medication at night will not eliminate the risk of interaction. Because the effects of grapefruit last a long time, they cannot be avoided by spacing medication and grapefruit apart. The effects of grapefruit can last up to 3 days, sometimes even longer. Food and Drug Administration that can have negative interactions with grapefruit. Grapefruit contains substances that can interfere with the transformation and elimination mechanisms of certain drugs when they are administered orally, resulting in serious adverse reactions.Īs little as 200 mL of juice or a whole grapefruit can cause a significant increase of blood levels of certain drugs. Currently, there are more than fifty prescription and over-the-counter drugs known to the U.S. Grapefruit and its juice (fresh or frozen) can either increase or, less frequently, decrease the effects of some drugs.
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